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Functional Red Yeast Rice

Twin Horse Biotech is a world-leading manufacturer of 100% naturally fermented red yeast rice, with customizable Monacolin K content from 0.03% to 5%.Our red yeast rice is clinically proven to support cholesterol reduction by inhibiting natural production and competing with dietary fats. With zero citrinin and zero liver toxicity, it ensures both safety and efficacy.

Monacolin K Specifications

Red yeast rice is a product of ancient Chinese medicinal wisdom, emerges as a beacon of natural health through the fermentation of a specific strain of yeast (Monascus purpureus) on rice. Red yeast rice is a source of monacolin K (also known as lovastatin, the active pharmaceutical ingredi-ent in Mevacor) (U.S. Food and Drug Administration, 2023).

Lovastatin Monacolin K
Essence Chemical Compound Naturally Fermented
Function Lipid-lowering Lipid-lowering
Working Mechanism Inhibit HMG-CoA Inhibit HMG-CoA
Chemical Structure Lactone Form Lactone Form + Acid Form
Absorption Hydrolyzed by Hydroxyl Esterase Absorb Directly
Side-effect Adverse (e.g., Liver Toxicity, Rhabdomyolysis) 100% Natural (No Side-effect)
Property Single Compound Various Bioactive Compounds (e.g., GABA, Isoflavones)
Application Pharmaceuticals Food, Cosmetics, Health Supplement, Pharmaceuticals
Monacolin K: A Natural Alternative to Lovastatin

In 1987, the USFDA approved lovastatin for treating high cholesterol and heart disease. As the chemically identical active ingredient in lovastatin, Monacolin K has become a popular natural alternative for managing high cholesterol, particularly for individuals who are intolerant to statins.

Unlike synthetic lovastatin, which exists in lactone form, Monacolin K naturally occurs in its acid form during the fermentation of red yeast rice. This is why it is often referred to as a "natural statin."

Due to its unique acid form, Monacolin K does not require hydrolysis by hydroxyl esterases to become bioactive, yet it functions in the same way as lovastatin. This reduces the strain on the liver while effectively lowering circulating cholesterol and LDL levels.

Beyond Monacolin K:

In addition to Monacolin K, red yeast rice contains other bioactive compounds such as monounsaturated fatty acids, GABA, and isoflavones—components that are not found in chemically synthesized lovastatin. These compounds promote overall cardiovascular health, support the immune system, and improve sleep and microcirculation—offering benefits beyond cholesterol management.

Twin Horse International Certificates

The products also conform to dietary requirements from cultures and religions; for example, Islamic and Jewish food specifications. The Twin Horse products prove the product standards of the US and EU regarding keeping the strict standards of organic products without any addition of chemicals and synthetics. This will finally make it possible to enter major global markets with wide recognition and trust.

Meanwhile, all products passed GBT19001, GBT24001 and ISO22000 quality and environment management system authentication to make the products more reliable.

Products manufactured by Twin Horse are of premium quality and have undergone the most strict criteria of manufacturing, having international product certifications such as the Halal Certificate, Kosher Certificate, USDA Organic Certification, and Organic Standard Certification CE-OS of the European Union.

Production Process

Sterilization Methods

We have two sterilization methods along with the corresponding processes and equipment: irradiation sterilization and high-temperature sterilization. Irradiation sterilization can retain as much Monacolin K in acid form as possible, while high-temperature sterilization can avoid Cobalt-60 residues. Customers can choose flexibly.

Small Tank Solid-State Fermentation

The small-tank solid-state fermentation process has higher visualization, more flexibility, and stronger monitorability. Under conditions of constant temperature and humidity and in light-proof conditions, our operators check the fermentation condition of each tank every day. In this way, each tank can timely monitor the raw materials and prevent a single potential source of contamination from affecting the whole batch.

Inoculation

In the inoculation process of TWIN HORSE, we use our own patented strain Mr-99, which can stably and efficiently produce high levels of Monacolin K during the fermentation process. Mr-99 controls the extremely low output of citrinin and can also produce abundant collateral metabolites,e.g. amino acids, unsaturated fatty acids, y-aminobutyric acid, isoflavones and other physiological active substances.

Our Core Strengths

Our company was established in 1999. It is the first red yeast rice manufacturer in China. We have led the formulation of red yeast rice industry standards and have 25 years of production and export experience. We have become a leading company in the red yeast rice industry, and our products are exported to Europe, America and Southeast Asia.

Our company can produce red yeast rice raw materials, health products and medicines. We cooperate with the Zhejiang Provincial Health Department and Zhejiang Provincial Hospital of Traditional Chinese Medicine to conduct human clinical trials. We have the national invention patent exclusive strain Mr-99, which has the characteristics of high temperature resistance, fast growth rate, low citrinin and high lovastatin content.

Global Trade

Our products are sold all over the world and are suppliers to customers such as Mylan, Pharmanex, Nu Skin, LCM, Swisse, and Byhealth.

Capacity advantage

We are China and are the only company in China that integrates the production of red yeast rice raw materials, health products and medicines.

Company History

Founded in 1999, we are the first red yeast rice producer in China and the formulation and drafting unit of red yeast rice industry standards.

Exclusive strains

We have an exclusive strain Mr-99, this strain has the characteristics of high yield of extracellular polysaccharides, high temperature resistance, fast growth, extremely low citrinin production.

Fermentation process

Using small tank solid fermentation technology, the fermentation process is strictly controlled in temperature, humidity and light avoidance, and the whole process is visually monitored.

Planting base

We have our own 1,000-acre high-quality non-GMO rice planting base, strictly controlling product quality from the source to ensure the purity and traceability of raw materials.

Get the solution

As a leading brand in the red yeast rice industry, we are committed to providing you with high-quality, efficient and safe red yeast rice products. If you have any needs or questions, please contact us for more detailed information!

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